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PICU DRUG INFORMATION
Adenosine
Antiarrhythmic
SVT
IV/IO:
Initially: 0.1 mg/kg (maximum: 6 mg/dose)
if no response in 2 min: 0.2 mg/kg (maximum: 12 mg/dose)
Not effective for atrial fibrillation/flutter or ventricular fibrillation. Adverse effects such as dyspnea, arrhythmias, bradycardia, flushing, sinus and AV block are very common but are usually transient due to short (10 seconds) half-life of drug.
Administration: Give rapid IV bolus followed by rapid saline flush.
Pharmacology: Slows A-V node conduction by blocking AV node re-entry pathways and suppressing atrial and Purkinjie tissue automaticity. Very short t ½ (10 seconds).
Updated: 12/21/2022
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