Pediatric Drug Dosing Reference

PICU DRUG INFORMATION


Cosyntropin

Adrenal function testing agent


ACTH stimulation test to assess adrenal function: High dose
IV:
15 microgram/kg (maximum: 250 microgram) once
Measure cortisol prior to, and 60 min post injection

ACTH stimulation test to assess adrenal function: Low dose
IV:
1 microgram once
Measure cortisol prior to, and 30 min post injection



Pharmacology: Stimulates the adrenal cortex to secrete adrenal steroids including cortisol.

Updated: 12/21/2022

Contact Information: This resource is maintained by Mark Duffett (duffett@hhsc.ca), Jon Wong (wongjon@hhsc.ca), and Nicole Clarke (clarken@hhsc.ca)
Disclaimer: This document has been created specifically for Hamilton Health Sciences (HHS) to use for its own patients and the information contained herein may not be applicable or relevant to other health care organizations. This document is for informational purposes only and is not intended to be a substitute for medical or clinical advice from a qualified health care professional. HHS makes no representations or warranties as to the accuracy of the information. This material is current only to the date listed. This material is the intellectual property of HHS and may not be shared, duplicated, or distributed further without the consent of HHS. HHS assumes no liability for the use of this information by the recipient.