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PICU DRUG INFORMATION
Amphotericin B (Liposomal)
Antifungal (lipid formulation of amphotericin B)
IV:
3-5 mg/kg (maximum: Can be increased to 10 mg/kg/DAY in selected cases) Q24H
Monitor renal function and electrolytes (particularly potassium and magnesium). Infusion-related adverse effects (e.g. fever, rigors etc) may require pre-treatment with acetaminophen and diphenhydrAMINE. Requires ID endorsement.
Pharmacology: Active against many Candida species, Aspergillus and most Mucor.
Updated: 12/21/2022
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