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PICU DRUG INFORMATION
Acetaminophen
Analgesic and antipyretic
Pain or fever
PO:
10-15 mg/kg (usual maximum: 75 mg/kg/day) Q4-6H PRN or Scheduled
PR:
10-20 mg/kg (usual maximum: 75 mg/kg/day) Q4-6H PRN or Scheduled
Give doses as needed or scheduled.
Administration: For rectal doses less than 80 mg, can administer acetaminophen 80 mg/mL drops rectally.
Pharmacology: Inhibits synthesis of prostaglandins. Reduces fever by direct effect on heat regulating centres to increase dissipation of body heat -Inhibits action of pyrogens on these centres. Blocks pain impulse generation in peripheral nervous system.
Updated: 05/22/2022
Disclaimer: This document has been created specifically for Hamilton Health Sciences (HHS) to use for its own patients and the information contained herein may not be applicable or relevant to other health care organizations. This document is for informational purposes only and is not intended to be a substitute for medical or clinical advice from a qualified health care professional. HHS makes no representations or warranties as to the accuracy of the information. This material is current only to the date listed. This material is the intellectual property of HHS and may not be shared, duplicated, or distributed further without the consent of HHS. HHS assumes no liability for the use of this information by the recipient.
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