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PICU DRUG INFORMATION
Aminophylline
Bronchodilator
Acute bronchospasm
IV:
6 mg/kg then:
2-6 months: 0.4-0.5 mg/kg/h
6-11 months: 0.6-0.7 mg/kg/h
1-12 years: 0.8-1 mg/kg/h
>12 years: 0.7 mg/kg/h
Base dose on ideal body weight.
Administration: Continuous infusion mixture:
<10 kg: 250 mg in 50 mL NS (5 mg/mL)
10-39 kg: 500 mg in 50 mL NS (10 mg/mL)
≥40 kg: 500 mg in 50 mL NS (10 mg/mL)
Draw level 12-24 hours after initiation of continuous infusion. Target serum level is 10-15 mg/L (55-83 micromol/mL). Drug interactions are common, including ciprofloxacin, clarithromycin, erythromycin.
Updated: 05/22/2022
Disclaimer: This document has been created specifically for Hamilton Health Sciences (HHS) to use for its own patients and the information contained herein may not be applicable or relevant to other health care organizations. This document is for informational purposes only and is not intended to be a substitute for medical or clinical advice from a qualified health care professional. HHS makes no representations or warranties as to the accuracy of the information. This material is current only to the date listed. This material is the intellectual property of HHS and may not be shared, duplicated, or distributed further without the consent of HHS. HHS assumes no liability for the use of this information by the recipient.
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