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GENERAL PEDIATRICS DRUG INFORMATION
Acetaminophen
Analgesic and antipyretic
Pain or fever
PO:
10-15 mg/kg (maximum: 4 g/day) (usual maximum: 75 mg/kg/day) Q4-6H PRN or Scheduled
PR:
10-20 mg/kg (maximum: 4 g/day) (usual maximum: 75 mg/kg/day) Q4-6H PRN or Scheduled
Give doses as needed or scheduled.
Administration: For rectal doses less than 80 mg, can administer acetaminophen 80 mg/mL drops rectally.
Pharmacology: Inhibits synthesis of prostaglandins. Reduces fever by direct effect on heat regulating centres to increase dissipation of body heat -Inhibits action of pyrogens on these centres. Blocks pain impulse generation in peripheral nervous system.
Updated: 05/22/2022
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