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GENERAL PEDIATRICS DRUG INFORMATION
Amoxicillin
Penicillin derivative oral antibiotic
Acute otitis media - targeting Streptococcus pneumoniae (including empiric therapy)
PO:
80-90mg/kg/day (usual maximum: 3 g/DAY) divided BID
Community-acquired pneumonia - targeting Streptococcus pneumoniae (including empiric therapy)
PO:
80-90mg/kg/day (usual maximum: 3 g/DAY) divided TID
Group A strep pharyngitis
PO:
50 mg/kg (maximum: 1 000 mg/dose) daily for 10 days
or: 25 mg/kg (maximum: 1 000 mg/dose) BID for 10 days
Prophylaxis in asplenia
PO:
10 mg/kg (maximum: 250 mg/dose) BID
(if suspension is required)
Other infections
PO:
40-50 mg/kg/day divided Q8H
Pharmacology: Broad spectrum penicillin with bactericidal activity. Inhibits penicillin-binding proteins, preventing peptidoglycan synthesis in bacterial cell walls – this causes cell lysis.
Updated: 05/22/2022
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