Pediatric Drug Dosing Reference

GENERAL PEDIATRICS DRUG INFORMATION


Mesalamine


Ulcerative colitis, Crohn's disease
PO:
30-50 mg/kg/day (usual maximum: 4.8 g/DAY (Asacol) or 4 g/day (Pentasa)) divided BID-QID

PR:
1-4 g HS



Availability:
Asacol 400 mg EC tablets
Pentasa 500 mg ER tablets which can be split or dispersed in water – do not crush/chew granules
Salofalk 500 mg suppository
Salofalk 2 g and 4 g enema

Other formulations and brands available on discharge.

Pharmacology: Asacol deposits in terminal ileum to rectum. Pentasa works from duodenum to rectum.

Updated: 12/21/2022

Contact Information: This resource is maintained by Mark Duffett (duffett@hhsc.ca), Jon Wong (wongjon@hhsc.ca), and Nicole Clarke (clarken@hhsc.ca)
Disclaimer: This document has been created specifically for Hamilton Health Sciences (HHS) to use for its own patients and the information contained herein may not be applicable or relevant to other health care organizations. This document is for informational purposes only and is not intended to be a substitute for medical or clinical advice from a qualified health care professional. HHS makes no representations or warranties as to the accuracy of the information. This material is current only to the date listed. This material is the intellectual property of HHS and may not be shared, duplicated, or distributed further without the consent of HHS. HHS assumes no liability for the use of this information by the recipient.